Биофизика и медицинская физика

Background and Objectives: Bladder cancer is one of the ten most common cancers causing a high mortality rate. Photodynamic therapy (PDT) is one of the promising ways to treat this disease. To increase the effectiveness of PDT it is necessary to ensure selective delivery of photosensitizer to the tumor. Selective delivery systems such as nano- and microparticles of calcium carbonate in the polymorphic modification of vaterite are of great interest to solve this problem.

Background and Objectives: The method of identification of symbolic sequences associated with the genetic structure of biological objects using the principles of small-angle polarimetry is considered. This method of analyzing and visualizing symbolic sequences obtained by sequencing DNA fragments can be defined as small-angle polarimetry of phase-modulating structures associated with genetic information.

Background and Objectives: Currently, antimicrobial peptides are one of the main sources of alternative antibiotics because they can easily interact with bacterial peptidoglycan by penetrating or dissolving biofilms with minimal side effects. However, from a practical point of view, questions remain open about choosing the optimal method for obtaining and scaling the process of isolating peptides from insect biomass, as well as analyzing drug prototypes.

Background and Objectives: Impedance plethysmography and Doppler ultrasound, in most cases, are considered as independent methods for analyzing hemodynamics. This work shows the presence of similarities in the shape of pulse waves recorded by the two indicated methods at rest and during exercise tests. The dynamics of the volume and velocity of blood flow in the radial artery was studied at rest, during an occlusive test and a test with a deep breath.

Background and Objectives: Knowledge of the optical and thermal human tissues properties is essential for optimizing laser therapy and optical diagnostics. Most studies are carried out at room temperature of the sample. At the same time, it is known that the optical properties of biological tissues depend on temperature even in the physiological temperature range, that is, in the range of normal functioning of the body.