Izvestiya of Saratov University.

Physics

ISSN 1817-3020 (Print)
ISSN 2542-193X (Online)

For citation:

Tishkov A. S., Kamenskikh T. G., Galanga V. A., Bucharskaya A. B., Maslyakova G. N., Bashkatov A. N., Genina E. A., Kochubey V. I., Burov A. M., Tuchin V. V. Optimization of Phacoemulsification in Different Forms of the Cataract in the Patients with Diabetes Mellitus. Izvestiya of Saratov University. Physics , 2014, vol. 14, iss. 1, pp. 20-24. DOI: 10.18500/1817-3020-2014-14-1-20-24

This is an open access article distributed under the terms of Creative Commons Attribution 4.0 International License (CC-BY 4.0).
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Language: 
Russian
Heading: 
Physics
UDC: 
616.43; 616-0 08.9; 616.39
DOI: 
10.18500/1817-3020-2014-14-1-20-24

Optimization of Phacoemulsification in Different Forms of the Cataract in the Patients with Diabetes Mellitus

Autors: 
Tishkov Antonina Sergeevna, Saratov State Medical University named after V. I. Razumovsky
Kamenskikh Tatyana Grigor'evna, Saratov State Medical University named after V. I. Razumovsky
Galanga Vladimir Anatol'evich, Saratov State Medical University named after V. I. Razumovsky
Bucharskaya Alla Borisovna, Saratov State Medical University named after V. I. Razumovsky
Maslyakova Galina Nikiforovna, Saratov State Medical University named after V. I. Razumovsky
Bashkatov Alexey Nikolaevich, Saratov State University
Genina Elina Alekseevna, Saratov State University
Kochubey Vyacheslav Ivanovich, Saratov State University
Burov Andrey Mikhailovich, Institute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences (IBPPM RAS)
Tuchin Valery Viсtorovich, Saratov State University
Abstract: 

In this work, human lens pathology in different forms of the cataract was studied. Two hundred twenty patients with a cataract (220 eyes) were included in the study. Morphological, immunohystological and immunocytochemical investigations of both lens capsule and substance with antibodies to α- (α-А and α-В), β-, and γ- crystallines were carried out. Diabetic patients revealed a more pronounced expression of α- and β-B crystallin compared with a group of patients with age-related cataracts. Correlation between composition of the crystallines in a lens and its density was demonstrated. It is shown that the lower density of the lens nucleus in patients with diabetes allows lowering the power of ultrasound phacoemulsification as well as reducing the sonication time of eye tissues.

Key words: 
cataract
ultrasound phacoemulsification
diabetes mellitus
crystallins
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