Izvestiya of Saratov University.
ISSN 1817-3020 (Print)
ISSN 2542-193X (Online)


апконверсионные частицы

Effect of the Temperature of NaYF4 : Er,Yb Upсonversion Particles on the Formation of Luminescence

The intensity of upconversion luminescence depends nonlinearly on the excitation intensity. The aim of this work is to study the effect of the temperature of NaYF4:Er,Yb upconversion particles on the dependence of the luminescence intensity on the excitation intensity. The synthesized particles were observed to have the shape of a hexagonal prism with a width of about 440 nm and a height of 445 nm. The upconversion luminescence spectra were obtained in the temperature range of 22–55° C with the excitation intensity in the range of 1.5–9.4 W/cm2.

Toxicity of Upconversion Nanoparticles. Overview

Background and Objectives: The object of the study was the toxicity of upconversion nanoparticles. The aim is to overview the literature on the toxicity of various types of upconversion nanoparticles and to search for their maximum permissible concentration when administered to laboratory animals in vivo. Materials and Methods: The approach used has been the analysis of recent publications on the topic.

ТОКСИЧНОСТЬ АПКОНВЕРСИОННЫХ НАНОЧАСТИЦ. ОБЗОР.

В работе приведен обзор результатов исследований по выявлению токсичности различных типов апконверсионных наночастиц. Апконверсионные частицы являются перспективными для визуализации структуры биологических тканей и органов в люминесцентном свете, а также для использования при диагностике заболеваний и фотоиндуцированной терапии. Рассмотрены наночастицы с дополнительными оболочками или функционализированные при помощи покрытия поверхности адресными или фотоактивными молекулами, позволяющими создание частиц с несколькими модальностями.

Prospects For Application of Upconversion Particles NaYF4:Er,Yb for Phototherapy

Background and Objectives: Functionalized upconversion particles allow for photodynamic and photothermal therapy of tumor with simultaneous temperature monitoring and visualization of the area of treatment. Upconversion particles can increase the depth of therapeutic effects due to the high penetration depth of the required excitation radiation. That is why they are a promising material for the combined phototherapy and simultaneous monitoring of biological tissue heating.