Izvestiya of Saratov University.


ISSN 1817-3020 (Print)
ISSN 2542-193X (Online)

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Salem S. F., Tuchin V. V. Trapping of Magnetic Nanoparticles in the Blood Stream under the Influence of a Magnetic Field. Izvestiya of Saratov University. Physics , 2020, vol. 20, iss. 1, pp. 72-79. DOI: 10.18500/1817-3020-2020-20-1-72-79

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Trapping of Magnetic Nanoparticles in the Blood Stream under the Influence of a Magnetic Field

Salem Samia Farouk, Saratov State University
Tuchin Valery Viсtorovich, Saratov State University

Magnetic nanoparticles, as controlled drug carriers, provide tremendous opportunities in treating a variety of tumors and brain diseases. In this theoretical study, we used magnetic nanoparticles, such as Superparamagnetic Iron Oxide Nanoparticles (Fe3O4) (SPION). Due to their biocompatibility and stability, these particles represent a unique nanoplatform with a great potential for the development of drug delivery systems. This allows them to be used in medicine for targeted drug delivery, in magnetic resonance imaging and magnetic hyperthermia. In the work, the trapping mechanisms of magnetic nanoparticles moving in a viscous fluid (blood) in a static magnetic field are numerically studied. The equations of motion for particles in the flow are governed by a combination of magnetic equations for the permanent magnet field and the Navier–Stokes equations for fluid (blood). These equations were solved numerically using the COMSOL Multiphysics® Modeling Software.

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