Izvestiya of Saratov University.

Physics

ISSN 1817-3020 (Print)
ISSN 2542-193X (Online)

For citation:

Salem S. F., Tuchin V. V. Trapping of Magnetic Nanoparticles in the Blood Stream under the Influence of a Magnetic Field. Izvestiya of Saratov University. Physics , 2020, vol. 20, iss. 1, pp. 72-79. DOI: 10.18500/1817-3020-2020-20-1-72-79

This is an open access article distributed under the terms of Creative Commons Attribution 4.0 International License (CC-BY 4.0).
Published online: 
02.03.2020
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Language: 
English
Heading: 
Brief Communications
Article type: 
Short communication
UDC: 
532.542
DOI: 
10.18500/1817-3020-2020-20-1-72-79

Trapping of Magnetic Nanoparticles in the Blood Stream under the Influence of a Magnetic Field

Autors: 
Salem Samia Farouk, Saratov State University
Tuchin Valery Viсtorovich, Saratov State University
Abstract: 

Magnetic nanoparticles, as controlled drug carriers, provide tremendous opportunities in treating a variety of tumors and brain diseases. In this theoretical study, we used magnetic nanoparticles, such as Superparamagnetic Iron Oxide Nanoparticles (Fe3O4) (SPION). Due to their biocompatibility and stability, these particles represent a unique nanoplatform with a great potential for the development of drug delivery systems. This allows them to be used in medicine for targeted drug delivery, in magnetic resonance imaging and magnetic hyperthermia. In the work, the trapping mechanisms of magnetic nanoparticles moving in a viscous fluid (blood) in a static magnetic field are numerically studied. The equations of motion for particles in the flow are governed by a combination of magnetic equations for the permanent magnet field and the Navier–Stokes equations for fluid (blood). These equations were solved numerically using the COMSOL Multiphysics® Modeling Software.

Key words: 
magnetic nanoparticles
magnetism
blood
Newtonian fluid
permanent magnet
computational modelling
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Received: 
07.12.2019
Accepted: 
09.01.2020
Published: 
02.03.2020
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