Izvestiya of Saratov University.


ISSN 1817-3020 (Print)
ISSN 2542-193X (Online)

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Tuchina E. S., Tuchin V. V., Altshuler G. B., Yaroslavsky I. V. Photodynamic Influence of Red (625 nm) and Infra-Red (805 nm) Radiation on Bacteria P. Acnes Processed by Photosensitizes . Izvestiya of Sarat. Univ. Physics. , 2008, vol. 8, iss. 1, pp. 21-26. DOI: 10.18500/1817-3020-2008-8-1-21-26

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Photodynamic Influence of Red (625 nm) and Infra-Red (805 nm) Radiation on Bacteria P. Acnes Processed by Photosensitizes

Tuchina E. S., Saratov State University
Tuchin Valeriy Viktorovich, Saratov State University
Altshuler G. B., Palomar Medical Technologies
Yaroslavsky I. V., Palomar Medical Technologies

It was shown, that Propionibacterium acnes was rather subjected to action of red and infrared radiation. The effect of the given radiation amplified at this bacteria by various solutions of photosensitizes. The received results are considered from the point of view of an estimation of light action efficiency in a combination to photosensitizes at photodynamic therapy skin suppurative inflammation diseases.

  1. Ross E.V. Acne, Lasers and Light // Advances in Dermatology. 2005. Vol.21. P.1−32.
  2. Nitzan Y., Dror R., Ladan H., Malik Z., Kimel S., Gottfried V. Structure-activity relationship of porphyrines for photoinactivation of bacteria // Photochem. Photobiol. 1995. Vol.62. P.342–347.
  3. Papageorgiou P., Katsambas A., Chu A.. Phototherapy with blue (415 nm) and red (660 nm) light in the treatment of acne vulgaris // British. J. Dermatol. 2000. №142. P.973–978.
  4. Kjeldstad B., Johnsson A. An action spectrum for blue and near ultraviolet inactivation of Propionibacterium acnes: with emphasis on a possible porphyrin photosensitization // Photochem. Photobiol. 1986. Vol.43. P.67–70.
  5. Simpson N. Antibiotics in acne: time for a rethink // British. J. Dermatol. 2001. №144. P.225−227.
  6. Kawada A., Aragane Y., Sangen Y., Tezuka T. Acne phototherapy with a high-intensity, enhanced, narrow-band, blue light source: an open study and in vitro investigation // J. Dermatol. Sci. 2002. Vol.30. P.129−135.
  7. Hongcharu W., Taylor C.R., Chang Y. D. Topical ALAphotodynamic therapy for the treatment of acne vulgaris // J. Invest Dermatol. 2000. Vol.115. P.183−192.
  8. Tuchin V.V., Genina E.A., Bashkatov A.N., Simonenko G.V., Odoevskaya O.D. , Altshuler G.B. A pilot study of ICG laser therapy of acne vulgaris: Photodynamic and photothermolysis treatment // J. Lasers in Surg. and Med. 2003. Vol.33, №5. P.296−310.
  9. Genina E.A., Bashkatov A.N., Simonenko G.V., Odoevskaya O.D., Tuchin V.V., Altshuler G.B. Low-Intensity ICGLaser Phototherapy of Acne Vulgaris: A Pilot Study // J. Biomed. Opt. 2004. Vol.9, №4. P.828−834.
  10. Анфимова Н.А., Потекаев Н.Н., Ткаченко С.Б., Шугинина Е.А. Фотодинамическая терапия: патогенетическое обоснование эффективности при вульгарных угрях // Эксперим. и клин. дерматокосметология. 2005. №5. С.125−130.
  11. Mariwalla K., Rohrer T. Use of lasers and light-based therapies for treatment of acne vulgaris // J. Lasers in Surg. and Med. 2005. Vol.37. P.333−342.
  12. Ovchinnikov I.S., Shoub G.M., Tuchin V.V. Photodynamic effect of laser radiation and methylene blue on some opportunistic pathogenic microorganisms of oral cavity // Proc. SPIE. 2000. Vol.4001. P.390−392.
  13. Genina E.A., Bashkatov A.N., Sinichkin Yu.P., Kochubey V.I., Lakodina N.A., Altshuler G.B., Tuchin V.V. In vitro and in vivo study of dye diffusion into the human skin and hair follicles // J. Biomed. Opt. 2002. Vol.7. P.471−477.