Izvestiya of Saratov University.

Physics

ISSN 1817-3020 (Print)
ISSN 2542-193X (Online)


For citation:

Navolokin N. A., Matveeva O. V., Maslyakova G. N., Bucharskaya A. B., Suleymanova L. V., Kun S. M., Medvedev B. A., Ignatiev A. A., Bochkaryeva Т. V. Morphological Changes in the Internal Organs of Laboratory Animals under a Single Administration of Fe Nanoparticles. Izvestiya of Sarat. Univ. Physics. , 2011, vol. 11, iss. 2, pp. 62-66. DOI: 10.18500/1817-3020-2011-11-2-62-66

This is an open access article distributed under the terms of Creative Commons Attribution 4.0 International License (CC-BY 4.0).
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Russian
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537.622.4:57.085:591.4:599.323.4:576.6;576.33:577.29:615

Morphological Changes in the Internal Organs of Laboratory Animals under a Single Administration of Fe Nanoparticles

Autors: 
Navolokin Nikita Aleksandrovich, Saratov State Medical University named after V. I. Razumovsky
Matveeva Olga Viktorovna, Saratov State University
Maslyakova Galina Nikiforovna, Saratov State Medical University named after V. I. Razumovsky
Bucharskaya Alla Borisovna, Saratov State Medical University named after V. I. Razumovsky
Suleymanova Leila Vakhidovna, Saratov State Medical University named after V. I. Razumovsky
Kun Syan Miao, Saratov State Medical University named after V. I. Razumovsky
Medvedev Boris Abramovich, Saratov State University
Ignatiev Alexander Anatol'evich, Saratov State Medical University named after V. I. Razumovsky
Bochkaryeva Тat'jana Vladimirovna, Saratov State University
Abstract: 

The cytotoxic effect of iron nanoparticles of size of 70 nm was studied in an experiment with single intramuscular and oral administration in albino mice and rats. Morphological changes were assessed in the internal organs, brain and the injection site. Studies had shown that intramuscular changes are more pronounced than when nanoparticles were administered orally and were shown in signs of cell damage while after the oral administration the blood flow changes in vessels were noted.

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