Izvestiya of Saratov University.

Physics

ISSN 1817-3020 (Print)
ISSN 2542-193X (Online)

For citation:

Prokhorova V. D., Kutikova O. Y., Palaguta A. M., Skripal A. V., Ermishin D. V., Rytik A. P. Study of the influence of electrical impulses on arterial blood microcirculation using laser Doppler flowmetry. Izvestiya of Saratov University. Physics , 2025, vol. 25, iss. 3, pp. 333-342. DOI: 10.18500/1817-3020-2025-25-3-333-342, EDN: OQWITA

This is an open access article distributed under the terms of Creative Commons Attribution 4.0 International License (CC-BY 4.0).
Published online: 
29.08.2025
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Language: 
Russian
Heading: 
Biophysics and medical physics
Article type: 
Article
UDC: 
530.182:537.86
DOI: 
10.18500/1817-3020-2025-25-3-333-342
EDN: 
OQWITA

Study of the influence of electrical impulses on arterial blood microcirculation using laser Doppler flowmetry

Autors: 
Prokhorova Veronika Dmitrievna, Saratov State University
Kutikova Oksana Yu., Saratov State University
Palaguta Alexey Mikhailovich, Saratov State University
Skripal Anatoliy Vladimirovich, Saratov State University
Ermishin Dmitry V., Clover LLC
Rytik Andrey Petrovich, Saratov State University
Abstract: 

Background and Objectives: The influence of low-voltage electrical current impulses on arterial blood microcirculation was investigated using the method of laser Doppler flowmetry. Materials and Methods: The method involves measuring the blood microcirculation index by quantifying the Doppler frequency shift arising when the microcirculatory bed is probed with laser radiation, followed by the registration of radiation reflected from both moving and stationary tissue components. Results: It has been demonstrated that exposure to electrical current impulses leads to an average 4-fold increase in the myogenic component of the spectrum relative to the baseline sample. This increase is associated with changes in the tone of the vascular wall in blood arterioles. The predominance of neurogenic components of the spectrum after cessation of exposure to electrical impulses has also been revealed. Conclusion: Utilizing the laser Doppler flowmetry method based on the amplitudes of spectral harmonics of vascular oscillation rhythms allows to determine quantitatively the changes in blood flow regulation during exposure to current impulses.

Key words: 
laser Doppler flowmetry
electrical impulses
blood microcirculation
arterial vessels
muscle tone
Acknowledgments: 
The work was supported by the Russian Science Foundation (project No. 23-14-00287, https://rscf.ru/project/23-14-00287/).
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Received: 
16.04.2025
Accepted: 
10.07.2025
Published: 
29.08.2025
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