Izvestiya of Saratov University.
ISSN 1817-3020 (Print)
ISSN 2542-193X (Online)


железо

Morphological Changes in the Internal Organs of Laboratory Animals under a Single Administration of Fe Nanoparticles

The cytotoxic effect of iron nanoparticles of size of 70 nm was studied in an experiment with single intramuscular and oral administration in albino mice and rats. Morphological changes were assessed in the internal organs, brain and the injection site. Studies had shown that intramuscular changes are more pronounced than when nanoparticles were administered orally and were shown in signs of cell damage while after the oral administration the blood flow changes in vessels were noted.