Izvestiya of Saratov University.
ISSN 1817-3020 (Print)
ISSN 2542-193X (Online)


optical clearing

Dehydration of Biotissues During Their Compression

Background and Objectives: Dehydration of tissue is one of the possible mechanisms of mechanical tissue optical clearing. In this study we investigated the effects of dehydration of ex vivo cow muscle tissue samples during their compression on diffuse reflectance spectra of the tissue. The purpose of research was to identify the correlation between the diffuse reflectance of the tissue and its dehydration.

Optical Clearing of Human Eye Sclera by Aqueous 30%-Glucose Solution

In this work, optical clearing of human eye sclera in vitro under action of aqueous 30% glucose solution was studied. It was shown that diffusion of glucose in tissue results in significant decrease of light scattering, which manifests itself in both decreasing reflectance and increasing transmittance of the samples. At that, absorption coefficient does not change. Measurements were performed with spectrophotometer CARY-2415 in the spectral range from 400 to 800 nm by a standard method.

Optical Clearing as Method to Increase the Depth of Nanoparticles Detection in the Skin with OCT-Visualization

Background and Objectives: Nanoparticles of titanium dioxide are now widely used both for the creation of sunscreen filters, and as carriers of drugs. One of the ways of transepidermal delivery of these nanoparticles to the dermis of the skin is their penetration into the hair follicles. However, optical control of the filling of follicles with nanoparticles is rather difficult due to strong light scattering in the skin.