Izvestiya of Saratov University.
ISSN 1817-3020 (Print)
ISSN 2542-193X (Online)


immunoglobulin

Spectral manifestations of amino acids from immunoglobulin and tumor necrosis factor composition intermolecular interaction and effect of cyanine 7 on this interaction

Immunoglobulin and tumor necrosis factor complex formation, which is the basis of immunosuppressive drug etanercept therapeutic action, has been studied using quantum chemical modeling and molecular dynamics. The effect on the possibility of cyanine 7 on hydrogen bonds formation between amino acids from tumor necrosis factor and immunoglobulin has been considered.