Izvestiya of Saratov University.

Physics

ISSN 1817-3020 (Print)
ISSN 2542-193X (Online)


For citation:

Ishbulatov Y. M., Simonyan M. A., Karavaev A. S., Kiselev A. R., Gridnev V. I. Decrease of low-frequency spectral power in a heart rate variability signal in a mathematical model of the cardiovascular system of arterial hypertension patients. Izvestiya of Sarat. Univ. Physics. , 2021, vol. 21, iss. 4, pp. 363-371. DOI: 10.18500/1817-3020-2021-21-4-363-371

This is an open access article distributed under the terms of Creative Commons Attribution 4.0 International License (CC-BY 4.0).
Published online: 
30.11.2021
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Language: 
Russian
Article type: 
Article
UDC: 
537.86.029

Decrease of low-frequency spectral power in a heart rate variability signal in a mathematical model of the cardiovascular system of arterial hypertension patients

Autors: 
Ishbulatov Yurii Mikhailovich, Saratov Branch of Kotel’nikov Institute of Radio Engineering and Electronics of the Russian Academy of Sciences
Simonyan Margarita A., Saratov State Medical University named after V. I. Razumovsky
Karavaev Anatoly Sergeevich, Saratov State University
Kiselev Anton Robertovich, Saratov State University
Gridnev Vladimir Ivanovich, Saratov State Medical University named after V. I. Razumovsky
Abstract: 

Background and Objectives: Index equal to the spectral power of the low-frequency oscillations from the time series of the time intervals between the hearts contractions are often used when investigating the cardiovascular system. Experimental studies have shown that this spectral index was a preclinical marker of cardiovascular diseases, including arterial hypertension and diabetes. However, physiological understanding of this index, in particular, its relation to the tone of autonomic control is still largely not understood. Materials and Methods: This problem was studied using mathematical models of the cardiovascular system, which simulated a healthy subject and an arterial hypertension patient. Conclusion: The decrease in the power of low-frequency oscillations in the time-series of the time intervals between the heart contractions in arterial hypertension patients was due to decreased dynamic range of the arterial baroreceptors.

Acknowledgments: 
This study was funded by the Russian Science Foundation (project No. 21-71-30011).
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Received: 
06.09.2021
Accepted: 
15.10.2021
Published: 
30.11.2021