Izvestiya of Saratov University.

Physics

ISSN 1817-3020 (Print)
ISSN 2542-193X (Online)

For citation:

Ten G. N., Plaksin M. I. Application of Au10 gold nanoclusters to block the formation of DNA from non-canonical forms. Izvestiya of Saratov University. Physics , 2025, vol. 25, iss. 2, pp. 157-166. DOI: 10.18500/1817-3020-2025-25-2-157-166, EDN: TCANCU

This is an open access article distributed under the terms of Creative Commons Attribution 4.0 International License (CC-BY 4.0).
Published online: 
30.06.2025
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Language: 
Russian
Heading: 
Optics and spectroscopy. Laser physics
Article type: 
Article
UDC: 
543.421
DOI: 
10.18500/1817-3020-2025-25-2-157-166
EDN: 
TCANCU

Application of Au10 gold nanoclusters to block the formation of DNA from non-canonical forms

Autors: 
Ten Galina Nikolaevna, Saratov State University
Plaksin Mikhail I., Saratov State University
Abstract: 

Background and Objectives: The objects of this study are gold nanoclusters and nucleic acid bases. The aim of the work is to study the interaction of gold plates, for which gold neutral flat 2D clusters (n = 10) were selected, with canonical and rare tautomeric forms of nucleic acid bases (BNA), as well as complementary pairs of Ade-Thy and Gua-Cyt. Materials and Methods: Calculations of the structure and vibrational spectra have been performed by the DFT method using the Gaussian-09 program. Results: The different character of interaction of gold Au10 nanoclusters with rare forms of nucleic acid bases has been observed. Conclusion: This feature leads to the formation of covalent bonds between them, which makes it possible to block or limit the uncontrolled process of DNA formation from non-canonical forms.

Key words: 
gold clusters
nucleic acid bases
canonical and rare forms
hydrogen and covalent bond energy
IR spectra
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Received: 
24.11.2024
Accepted: 
17.02.2025
Published: 
30.06.2025
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