Для цитирования:
Ульянов С. С., Ульянова О. В., Зайцев С. С., Салтыков Ю. В., Ульянов А. С., Федорова В. А. Интерференция GB-спеклов в молекулярной дискриминации бактериальных патогенов: использование метода s-LASCA на модели Chlamydia psittaci // Известия Саратовского университета. Новая серия. Серия: Физика. 2021. Т. 21, вып. 4. С. 315-328. DOI: 10.18500/1817-3020-2021-21-4-315-328, EDN: QTABPN
Интерференция GB-спеклов в молекулярной дискриминации бактериальных патогенов: использование метода s-LASCA на модели Chlamydia psittaci
Продемонстрировано, как виртуальные оптические спеклы (GB-спеклы) могут быть сформированы из нуклеотидных последовательностей семи генов домашнего хозяйства Chlamydia psittaci. Изучены специфические особенности формирования интерференционных картин при суперпозиции как исходных GB-спеклов, так и GB-спеклов, прошедших обработку методом анализа контраста лазерных спеклов (s-LASCA). Показано, что контраст интерферирующих GB-спеклов может быть использован для выявления полиморфизма у нуклеотидных последовательностей бактериальных патогенов, используемых для мультилокусного типирования.
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